Neurobion Is an anti-inflammatory, analgesic, antineuritic and anti-neuralgic drug. In other words, Neurobion is a drug that is used a lot to combat inflammation of the tissues, the sensation of pain, the inflammation of the nerves and the neuralgias, that is to say, those continuous but not necessarily inflammatory pains that extend in a nerve Specific and in their respective ramifications. Neurobion comes in ampoules, dragees or capsules.
Although the amounts and additional ingredients may vary according to the presentation (some have substances such as diclofenac sodium, excipients, etc.), Neurobion is characterized mainly by having Vitamin B1 (common name given to thiamine nitrate), Vitamin B6 (Ibid, but to pyridoxine hydrochloride) and Vitamin B12 (ibid, but cyanocobalamin). This composition comprises each dragee, capsule or ampoule separately.
Pharmacology
The pharmacological action of Neurobion occurs in three ways. In Vitamin B1, it contributes to solve the lack of thiamine in the body, which is responsible for the lactic acid that accumulates in the body and affects muscle, circulatory, bone and nervous performance.
Vitamin B6 compensates for the lack of pyridoxine that causes nerve problems, apart from other tissue injuries. In Vitamin B12, for its part, it is useful to reduce the neurological damage that can happen in pathological degenerative processes.
Taken together, these three vitamins (ie, B1, B6 and B12), integrated in Neurobion, can regulate the metabolic activity of the enzymes, whose levels in the organism can be raised with an increase in the dose above the requirements newspapers. Both short-term and long-term changes are seen in the metabolism, which undergoes saturation and then a release of these enzymes (coenzymes and apoenzymes).
It is also possible that higher doses of Neurobion can eliminate or relieve pain, which is known as the analgesic effect.
In these cases, neuropathies can be relieved and damage done to nerve tissue can be repaired by stimulating the synthesis of nucleoproteins, that is, of compounds that combine proteins with nucleic acids DNA and RNA).
Indications
Neurobion is used as an adjunctive treatment for both neuritis and neuralgia, both of which are related to inflammation of the nerves.
It is also used in conditions such as rheumatism, arthritis, spondyloarthrosis (also known as EDD, or Degenerative Disc Disease), spondylitis (a form of chronic arthritis affecting one or more vertebrae of the spine) drop.
Dosage
The only way to take a correct dose of Neurobion is through a clinical diagnosis that accurately determines what type of discomfort the patient has.
However, in adults, the use of Neurobion in tablets or capsules is often prescribed one to three times per day, as prescribed by the doctor. Under no circumstances should the recommended dose be exceeded or increased, unless the specialist deems it necessary.
Contraindications
The administration of Neurobion is absolutely contraindicated in the following cases:
- Allergy or hypersensitivity to components.
- Patients with Parkinson's disease, provided they are taking levodopa alone.
- Children younger than 6 years (to see if the child over this age can or does not take Neurobion, consult your pediatrician).
- In the course of pregnancy and lactation.
- Renal or hepatic impairment.
- Disorders of the digestive system: gastritis, duodenal and gastric ulcers, esophagitis.
- Elderly elderly.
Adverse reactions
In higher doses than normal, Neurobion can cause alterations in the nervous system. Common reactions seen in patients include diarrhea, vomiting, nausea, fatigue, vertigo, and headache.
Only in very few cases has ulcerative colitis and digestive hemorrhages worsened, as well as irritability, seizures, insomnia, Tinnitus , Urticaria and momentary reddening of the skin (rashes).
There are also rare or exceptional cases of reactions to Neurobion, such as photosensitivity, hair loss (alopecia), kidney failure, liver dysfunction, inflammation of the kidneys (nephritis) and blood in the urine (hematuria). This list also includes a number of additional conditions, such as leukocytosis (leucopenia), reduction of platelets (thrombocytopenia) and anemia, among others.
Precautions
Before consumption by the patient, Neurobion medication requires these considerations and preventive measures, which will be studied in one case or another by the physician weighing the pros and cons of this drug:
- The contraindications of Neurobion, with its adverse reactions and interactions (see sections 4, 5 and 7 of this article).
- Presence of disorders related to the central nervous system, which may prevent the patient from concentrating on the use of machines or driving vehicles.
- Existence of celiac disease and diabetes in the patient (there are presentations of this drug containing gluten and sugar).
Interactions
Neurobion has reactions with drugs and other substances, such as paracetamol, insulin, heparin, valproic acid and levodopa.
The various interactions of Neurobion can have consequences on the efficacy of medications already being taken and also on the patient's health.
This article is only intended to give general information about Neurobion, hence there will be no widespread use of pharmaceutical terminology. Since Neurobion is a product that comes in different presentations, it will be spoken about globally. It should be noted that Neurobion is a registered trademark in the name of Merck, so this writing is not an official publication of the company and its author does not act on behalf of it.
This means that you should consult a specialist beforehand if you have an illness that can be treated with Neurobion; Do not take if you do not need it or if your doctor has not told you to. It is also important to limit what the brochures that are printed on all medicines say: it is necessary that you always go to the doctor if there are adverse effects, if you have allergy to any of its components and if you are pregnant or breastfeeding. See the references section for more details.]
References
- Dolo Neurobion® [Online article]. Lima Peru. Peruvian Society of Cardiology, Merck Peruana S.A. Accessed January 26, 2017, in: Sopecard.org
- Juárez, LM (No year). Pharmacological Review. Antianemic [Online article]. Mexico D.F., Mexico. National Autonomous University of Mexico, Department of Family Medicine. Accessed January 26, 2017, in: Facmed.unam.mx.
- McVan, Barbara (1995). Pharmaceutical References: a reference manual for health professionals (Francisco Balderrama Encimas, trans.). Mexico D.F., Mexico. Modern Manual.
- Neurobion® 5000. Merck [Online article] (2015). P.R.Vademécum [Web page]. Clyna S.A. Accessed January 26, 2017, in: Pe.prvademecum.com
- Neurobion Ampoules [Online article] (2017). Metn, Lebanon. HCP-Meppo. Accessed January 26, 2017, in: Meppo.com
- Neurobión - CECMED [Online article] (2014). Havana Cuba. Ministry of Public Health of Cuba; Center for State Control of Medicines, Medical Devices and Devices. Accessed January 26, 2017, in: Cecmed.cu.
- Neurobion - Merck Consumer Health [Online article] (2016). Darmstadt, Germany. Merck. Accessed January 26, 2017, in: Merck-consumer-health.com.
- Rodríguez Carranza, Rodolfo (1999). Academic Vademecum of medicines (3rd ed.). Mexico D.F., Mexico. McGraw-Hill Interamericana.